Also known as: Theanine, γ-glutamylethylamide
L-Theanine is an amino acid found primarily in green tea. It promotes relaxation without drowsiness, enhances focus, and is one of the best-studied compounds for reducing anxiety while maintaining cognitive clarity.
For focus: take in the morning with caffeine. For sleep: take 30–60 minutes before bed. Fast-acting (effects in 30–60 min).
Rapidly absorbed, crosses the blood-brain barrier within 30 minutes. Can be taken on an empty stomach.
As needed
Often paired with caffeine
Daily or as needed
30–60 min before bed
As needed
2:1 ratio of theanine to caffeine
Both promote relaxation and improve sleep quality. Great evening stack.
Complementary anxiety-reducing mechanisms. Effective anxiolytic stack.
Both support cognitive function and mood through different pathways.
Nobre AC, Rao A, Owen GN. - Asia Pacific Journal of Clinical Nutrition (2008)
L-theanine significantly increased alpha brain wave activity, indicating relaxation without sedation.
Owen GN, Parnell H, et al. - Nutritional Neuroscience (2008)
The combination improved speed and accuracy on attention tasks and reduced susceptibility to distracting information.